Efficacy of Montelukast combined with Sublingual Immunotherapy in the treatment of children with Obstructive Sleep Apnea Hypopnea Syndrome Complicated with allergic rhinitis

Objective: To observe the efficacy of Montelukast combined with sublingual immunotherapy (SLIT) in treatment children obstructive sleep apnea hypopnea syndrome (OSAHS) complicated allergic rhinitis (AR).
 Methods: This is a prospective study. A total 102 OSAHS admitted to Hunan Children’s Hospital from April 2020 2021 were selected and randomly divided into two groups: group two-drug combination group. Children treated standardized dust mite drops Nos. 1-4 for SLIT, while those on top Statistical analysis comparison made between groups terms Sleep index (AHI), Hypoxic saturation (Lsao2), interleukin-4, Il-4), interleukin-17 (IL-17), OSA-18 Snoring Symptom Scale (OSA-18), symptom scale (TNSS), efficacy, occurrence adverse reactions, etc.
 Results: After treatment, AHI was significantly decreased, Lsao2 increased compared (P<0.05). Compared group, levels IL-4 IL-17 decreased (P<0.05), score TNSS lower Moreover, incidence reactions (P<0.05).
 Conclusion: offers many advantages, such as effectively controlling nasal allergy symptoms improving symptoms.
 doi: https://doi.org/10.12669/pjms.39.5.6985
 How cite this: Mao X, Zhao W. Efficacy Sublingual Immunotherapy Obstructive Apnea Hypopnea Syndrome Complicated rhinitis. Pak J Med Sci. 2023;39(5):---------. an Open Access article distributed under Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, reproduction any medium, provided original work properly cited.